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Chemical Engineering

Publications - Cyberinfrasture for Pharmaceutical Engineering

Keywords-Hazard and Operability Analysis (HAZOP), Process Hazard Analysis (PHA), Expert Systems, Knowledge-Based Systems, Operating Procedure Synthesis (OPS)

A. Refereed Journal Publications

  1. S. Viswanathan, N. Shah, and V. Venkatasubramanian, "Hybrid Framework for Hazard Identification and Assessment in Batch Processes", AIChE J, 48(8), 1765-1774, 2002.

  2. V. Venkatasubramanian, J. Zhao, and S. Viswanathan, "Intelligent Systems for HAZOP Analysis of Complex Process Plants", Comput Chem Eng, 24(9-10), 2291-2302, 2000. (Download)

  3. S. Viswanathan, C. Johnsson, R. Srinivasan, V. Venkatasubramanian, and K. E. Arzen, "Automating Operating Procedure Synthesis for Batch Processes: Part I. Knowledge Representation and Planning Framework", Comput Chem Eng, 22(11), 1673-1685, 1998.  (Download)

  4. S. Viswanathan, C. Johnsson, R. Srinivasan, V. Venkatasubramanian, and K. E. Arzen, "Automating Operating Procedure Synthesis for Batch Processes: Part II. Implementation and Application", Comput and Chem Eng, 22(11), 1687-1698, 1998. (Download)

  5. R. Srinivasan and V. Venkatasubramanian, "Automating HAZOP Analysis of Batch Chemical Plants: Part I. The Knowledge Representation Framework", Comput and Chem Eng, 22(9), 1345-1356, 1998. (Download)

  6. R. Srinivasan and V. Venkatasubramanian, "Automating HAZOP Analysis of Batch Chemical Plants: Part II. Algorithms and Application", Comput and Chem Eng, 22(9), 1357-1370, 1998. (Download)

  7. R. Srinivasan, V. D. Dimitriadis, N. Shah, and V. Venkatasubramanian, "Safety Verification Using a Hybrid Knowledge-Based Mathematical Programming Framework", AIChE J, 44(2), 361-371, 1998.

  8. R. Vaidhyanathan and V. Venkatasubramanian, "A Semi-Quantitative Reasoning Methodology for Filtering and Ranking HAZOP Results in HAZOPExpert", J. of Rel. Engg. and Sys. Safety, 53(2), 185-203, 1996.

  9. R. Vaidhyanathan, V. Venkatasubramanian, and F. Dyke, "HAZOPExpert: An Expert System for Automating HAZOP Analysis," Process Safety Progress, 15(2), 80-88,1996.

  10. R. Vaidhyanathan and V. Venkatasubramanian, "Digraph-Based Models for Automated HAZOP Analysis", J. of Rel. Engg. and Sys. Safety, 50(1), 33-49, 1995.

  11. V. Venkatasubramanian and R. Vaidhyanathan, "A Knowledge-Based Framework for Automating HAZOP Analysis", AIChE J, 40(3), 496-505, 1994.  


B. Refereed Publications in Conference Proceedings
  1. C. Zhao, G. Joglekar, A. Jain, V. Venkatasubramanian, G. V. Reklaitis, “Pharmaceutical Informatics: A Novel Paradigm for Pharmaceutical Product Development and Manufacture” Proceedings of ESCAPE-15, 2005. (Download)

  2. C. Zhao, V. Venkatasubramanian, “Learning in Intelligent Systems for Process Safety Analysis ” Proceedings of ESCAPE-15, 2005. (Download)

  3. C. Zhao, Y. Shimada, V. Venkatasubramanian, “An Integrated System to Support Design of Safer Batch Processes” Proceedings of ESCAPE-14, 2004. (Download)

  4. C. Zhao, M. Bhushan, V. Venkatasubramanian, “A Multi-Agent Architecture for Automated Process Safety Analysis”, Proceedings of 8th International Symposium on Process Systems Engineering, China, 2003. (Download)

  5. C. Zhao, M. Bhushan, V. Venkatasubramanian, “Roles of Ontology in Automated Process Safety Analysis”, Proceedings of ESCAPE-13, Finland, 2003. (Download)

  6. V. Venkatasubramanian, J. Zhao, S. Viswanathan, C. Zhao, F. Mu, P. M. Harper. B. M. Russel, "An Integrated Environment for Batch Process Development – From Recipe to Manufacture", 925- 930, Proceedings of ESCAPE-11, Denmark, 2001. (Download)

  7. J. Zhao, S. Viswanathan, C. Zhao, F. Mu, V. Venkatasubramanian, "Knowledge-based Management of Change in Chemical Process Industry", 931-936, Proceedings of ESCAPE-11, Denmark, 2001.

  8. J. Zhao, S. Viswanathan, C. Zhao, F. Mu, and V. Venkatasubramanian, "Computer-Integrated Tools for Batch Process Development", Comput Chem Eng, 24 (2-7), Proceedings of the Process Systems Engineering Conference (PSE 2000), 1529-1533, 2000. (Download)

  9. J. Zhao, S. Viswanathan and V. Venkatasubramanian, "Industrial Applications of Operating Procedure Synthesis and Process hazards Analysis for Batch Plants", Computer Aided Chem Eng, 8 (Proceedings of ESCAPE-10), 787-792, 2000 (Download)

  10. S. Viswanathan, N. Shah, and V. Venkatasubramanian, "A Hybrid Strategy for Batch Process Hazards Analysis", Comp Chem Eng, 24(2-7), Proceedings of the Process Systems Engineering Conference (PSE 2000), 545-549, 2000.

  11. S. Viswanathan, J. Zhao, and V. Venkatasubramanian, "Integrating Operating Procedure Synthesis and Hazards Analysis Automation Tools for Batch Processes", Comput Chem Eng, 23(Proceedings of ESCAPE-9), S747-S750, 1999. (Download)

  12. S. Viswanathan, L. Mockus, V. Venkatasubramanian, P. K. Basu, R. Mack, P. Cherukat, and V. Iskos, "iTOPS: An Intelligent Tool for Operating Procedure Synthesis", Comput Chem Eng, 22(Proceedings of ESCAPE-8), S601-S608, 1998.

  13. R. Srinivasan and V. Venkatasubramanian, "Multi-Perspective Models for Process Hazards Analysis of Large Scale Chemical Processes", Comput Chem Eng, 22(Proceedings of ESCAPE-8), S961-S964, 1998.

  14. R. Srinivasan and V. Venkatasubramanian, "PHAZer: An Intelligent System for Automated Process Hazards Analysis", in the Proceedings of International Conference of Risk Analysis in Process Safety, Atlanta, GA, Oct 21-24, 1997.

  15. R. Srinivasan, V. D. Dimitriadis, N. Shah, and V. Venkatasubramanian, "Integrating Knowledge-Based and Mathematical Programming Approaches for Process Safety Verification", Comput Chem Eng, 21(Proceedings of ESCAPE-7), S905-S910, 1997.

  16. R. Vaidhyanathan and V. Venkatasubramanian, "Experience with an Expert System for Automated HAZOP Analysis", Comput Chem Eng, 20(Proceedings of ESCAPE-6), S1589-S1594, 1996. (Download)

  17. R. Srinivasan and V. Venkatasubramanian, "Petri Net-Digraph Models for Automating HAZOP Analysis of Batch Process Plants", Comput Chem Eng, 20(Proceedings of ESCAPE-6), S719-S725, 1996. (Download)

  18. C. Johnsson, S. Viwanathan, R. Srinivasan, V. Venkatasubramanian, and K. E. Arzen, "A Model-Based Framework for Automating Operating Procedure Synthesis for Batch Chemical Processes", in the Proceedings of the Process Plant Safety Symposium, Houston, TX, April 1996.

  19. R. Vaidhyanathan and V. Venkatasubramanian, "HAZOPExpert: An Intelligent System for Automated HAZOP Analysis", in the Proceedings of the Process Plant Safety Symposium, Houston, TX, April 1996.

  20. V. Venkatasubramanian and R. Vaidhyanathan, "HAZOPExpert: A Knowledge-Based System for HAZOP Analysis", in the Proceedings of the Fifth International Symposium on Process Systems Engineering (PSE 94), Kyongu, S. Korea, June 1994.


C. Papers presented at conferences and meetings

  1. C. Zhao, M. Bhushan, V. Venkatasubramanian, “A Collaborative Environment for Process Safety Analysis”, AIChE Annual Conference, Indianapolis, IN. 2002. 

  2. C. Zhao, M. Bhushan, V. Venkatasubramanian, “Knowledge Engineering Issues in Process Safety Analysis”, AIChE Annual Conference, Indianapolis, IN. 2002. 

  3. C. Zhao, F. Mu, V. Venkatasubramanian, “An Integrated Framework for Automated HAZOP Analysis and Its Implementation”, Proceedings of AIChE Batch Processing Topical Conference, Reno, NV. 2001.

  4. J. Zhao, S. Viswanathan, and V. Venkatasubramanian, "Safe Design of Operating Procedures", AIChE Annual Meeting, Dallas, TX, Nov 1999.

  5. S. Viswanathan, J. Zhao, and V. Venkatasubramanian, "Integrated System for Batch Process Development", AIChE Annual Meeting, Dallas, TX, Nov 1999.

  6. J. Zhao, S. Viswanathan, R. Srinivasan, V. Venkatasubramanian, P. Basu, A. Noren, J. M. Vinson, "Automated Process Hazards Analysis of Batch Chemical Plants", AIChE Annual Meeting, Miami, FL, November 1998.

  7. V. Venkatasubramanian, S. Viswanathan, P. Basu, L. Mockus, and J. M. Vinson, "Automated Batch Records generation for Pharmaceutical Plants", AIChE Annual Meeting, Miami, FL, November 1998.

  8. R. Srinivasan and S. Viswanathan, C. Johnsson, V. Venkatasubramanian and K-E. Arzen, "An Intelligent System for Operating Procedure Synthesis", AIChE Annual Meeting, Chicago, IL, November 1996.

  9. R. Vaidhyanathan and V. Venkatasubramanian, "Digraph-based Models for Automating the HAZOP Analysis of Chemical Plants", AIChE Annual Meeting, Miami, FL, November 1995.

  10. V. Venkatasubramanian and R. Vaidhyanathan, HAZOPExpert: A Model-Based System for HAZOP Analysis", AIChE Spring Meeting, Atlanta, April 1994.

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