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Bionanotechnology

Bionanotechnology is a rapidly emerging research topic that integrates biology with inorganic materials at a sub-micron scale for the design and fabrication of microfluidic devices. The Laboratory's work is addressing fundamental research on protein interactions at surfaces, proteins as templates to construct hybrid materials, and methods for rapid prototyping of microfluidic devices. The goal of the research is to enhance our base of fundamental knowledge so that complex biological fluids may be processed for purposes of rapid detection of microbial food pathogens and the detection of proteins that are biomarkers for various diseases. Click on the links below to view presentations by LORRE researchers in the bionanotechnology area.

Predicting Cell Capture from Dilute Samples for Microfluidic Biosensors
Mosier, N. S., Craig, B., Workshop on Overarching Issues in Risk Analysis, National Institute of Statistical Sciences, Ames, IA, October 28, 2005.

Nanotechnology and Press-fit Microdevices
Huang, T., D. Taylor, N. S. Mosier, M. Sedlak, and M. R. Ladisch, Novel Applications: Nanobiotechnology, 2nd World Congress on Industrial Biotechnology and Bioprocessing, Orlando, Florida, April 20, 2005.

Nanoscale, Enzyme Mimicking Catalysts for Bioprocessing Agricultural Residues
Mosier, N. S., Division of Agricultural and Food Chemistry, 229th ACS Annual Meeting, San Diego, CA, March 16, 2005.

Probability Distribution Model for Predicting Cell Capture from Dilute Solutions for Microfluidic Biosensors
Zang, Y., X. Liu, B. Tyner, A. Stewart, W.-T. Chen, M. Sedlak, N. S. Mosier, B. Craig, and M. R. Ladisch, Division of Biochemical Technology, Poster 341, 229th National ACS Meeting of the American Chemical Society, San Diego, CA, March 16, 2005.

Fundamentals of Nanotechnology in Agriculture
Ladisch, M. R., T. Huang, R. Armstrong, and N. Mosier, Division of Agricultural and Food Chemistry, Paper 205, 229th National ACS Meeting of the American Chemical Society, San Diego, CA, March 17, 2005.

Press-fit Microdevice for Detecting Pathogenic Bacteria
Huang, T., D. G. Taylor, X. Liu, M. Sedlak, N. S. Mosier, and M. R. Ladisch, Poster, Indiana Biosensor Conference, Indianapolis, Indiana, April 6, 2005.

Fundamentals of Nanotechnology: Relationship to Food Science and Technology
Huang, T., W. Chen, T. Geng, R. Gomez, R. Bashir, A. Bhunia, and M. R. Ladisch, Invited Lecture, Paper 45-1, 2004 Institute of Food Technologies Annual Meeting, Symposium: Nanoscale Science, Engineering and Technology for Food Safety and Engineering ", Las Vegas, NV, July 14, 2004.

Pathogen Capture and Concentration on Functionalized Polycarbonate Membrane Detection and Sample Preparation Based on Immuno-Filters
Chen, W.-T. (Speaker), M. R. Ladisch, T. Geng, and A. K. Bhunia, BIOT Division Paper 140, 227th ACS National Meeting, Section: High Throughput Screening/Genomics and Proteomics, Anaheim, CA (March 30, 2004).

Detection of Labeled Microbial Cells Using Microfluidic Biosensor
Huang, T., D. Taylor, M. Sedlak, G. Gregori, D. Akin, R. Bashir, M. R. Ladisch, and P. Robinson, BIOT Division, Paper 10, 227th ACS National Meeting, Section: Biosensors and Bioprocess Monitoring and Control, Anaheim, CA, March 28, 2004.

Fabrication of Microfluidic Channels Using Microfibers with Poly(dimethylsiloxane)
Huang, T., W.-J. Chang, D. Akin, R. Gomez, R. Bashir, N. Mosier, and M. R. Ladisch, Poster Session: Advances in Biosensors and Biomedical Sensors I, Paper 193a, AIChE National Meeting, San Francisco Hilton & Towers, San Francisco, CA, November 17, 2003.

A Novel Method to Detect Listeria monocytogenes with Bio-selective Membranes
Chen, W.-T., (Poster presenter), M. R. Ladisch, T. Geng, and A. K. Bhunia, BMES Annual Meeting, Nashville, TN, October 2003.

Biofunctional Membranes for Listeria monocytogenes Detection
BIOT Division Paper 112, 225th ACS National Meeting, Section: Advances in Bioseparations, New Orleans, March 25, 2003.

Bio-mediated Assembly of Functionalized Microbeads for Capture of Microorganisms
Huang, T., T. Geng, D. Akin, W. Chang, J. Sturgis, R. Bashir, A. K. Bhunia, J. P. Robinson, and M. R. Ladisch, BIOT Division Paper 97, 225th ACS National Meeting, Section: Novel Bioanalyses Using Lab-on-a-Chip Technologies, New Orleans, LA, March 24, 2003.

Transport of Fluids Using Microwicks in Microfluidic Devices
Huang, T., J. Sturgis, R. Bashir, J. P. Robinson and M. R. Ladisch, Paper 340c, AIChE National Meeting, Indianapolis Convention Center, Indianapolis, IN, November 6, 2002.

Rapid Sample Preparation of Foodborne Pathogens by Membrane Filtration
Chen, W.-T., R. Hendrickson, and M. Ladisch, BioMEMS and Biomedical Nanotechnology, Poster 24, Columbus, OH, September 6-8, 2002.

Composite Surface for Capture of Listeria monocytogenes on a Protein Biochip
Huang, T., J. Sturgis, R. Gomez, T. Geng, R. Bashir, A. K. Bhunia, J. P. Robinson, and M. R. Ladisch, BIOT Division Paper 24, 224th ACS National Meeting, Section: Bioanalyses in the Micro to Nano-flow Regime, Boston, MA, August 18-22, 2002.

Composite Surface for Protein Biochips
Huang, T., J. Sturgis, R. Gomez, T. Geng, R. Bashir, A. K. Bhunia, J. P. Robinson, and M. R. Ladisch, Poster 22, International Society for BioMEMS and Biomedical Nanotechnology (ISBBN) Meeting, Columbus, OH, September 6-8, 2002.

Rapid Separation and Concentration of Bacterial Pathogens in Liquid Food Samples
Chen, W.-T., (Speaker), R. Hendrickson, M. R. Ladisch, T. Geng, and A. K. Bhunia, BIOT Division Paper 77, 224th ACS National Meeting, Section: Advances in Bioseparations, Boston, MA, August 18-22, 2002.


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